The fact sheet on syphilis is for front-line, outreach staff, public health staff, others providing sexual health care, and the communities of gay, bisexual, queer, and other men who have sex with men (gbMSM). In Canada, gbMSM are disproportionately impacted by sexually-transmitted infections (STIs). The fact sheet provides information on what syphilis is, testing, treatment, and harm reduction, stigma of syphilis and sex, and a sex-positive message to validate and affirm gbMSM’s experiences and encourage them to effectively care for the sexual health of themselves and their partners.