We have just released new medication updates to the Guidelines for Gender-Affirming Primary Care with Trans and Non-Binary Patients. As evidence and clinical practice evolve, these updates are here to support you in delivering informed, evidence-based gender-affirming care.
The latest update focuses on injectable estradiol for feminizing hormone therapy.
Historically, recommendations for injectable estradiol have been based on limited evidence, leading to significant variation in dosing guidance. As the use of injectable estradiol continues to grow, emerging research is providing new insights to support more consistent, evidence-informed clinical practice.
You can download the guidelines with the most recent amendments from our website or purchase a print copy in our online shop.
Before consulting the main guidelines, please review the amendments. Where guidance differs, the updated recommendations supersede the original 2019 publication.